Complete nucleotide sequence of hepatitis B virus

Complete nucleotide sequence of hepatitis B virus isolated from two infants with fulminant hepatitis.

Kenji Abe*, Tetsuya Kiuchi, Naoto Aiba, Huy Thien-Tuan Tran, Xin Ding, Mari Yamaguchi, Tetsutaro Sata and Koichi Tanaka Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Department of Transplantation and Immunology, Kyoto University Faculty of Medicine, Kyoto 606-8501, Department of Developmental Medical Sciences, Graduate School of Medicine, University of Toky...

Mutations at Nucleotide 1762, 1764 and 1766 of Hepatitis B Virus X Gene in Patients with Chronic Hepatitis B and Hepatitis B-Related Cirrhosis

Abstract       Background and objective: Hepatitis B virus (HBV) is a DNA virus with high tendency toward hepatic tissue. There are currently about 3 million HBV-infected people and 350 to 400 million chronic carriers of this virus in the world. X protein plays a role in the over-expression of oncogenes, carcinogenicity of liver cells and overlaps with the basal co...

commentary on: a study of genotypes, mutants, and nucleotide sequence of hepatitis b virus in pakistan

Sequence-based genotyping of hepatitis B virus in general popula-tion

    Background: Hepatitis B Virus (HBV) causes acute and chronic liver disease worldwide. HBV has eight genotypes (A to H) which is the reflection of its genome with their characteristic geographical distribution. Each genotype could have different pathogenic and therapeutic characteristics. There have been few records on HBV genotyping in general population from our region. This study aimed to...

Mutations in core nucleotide sequence of hepatitis B virus correlate with fulminant and severe hepatitis.

Infection with hepatitis B virus leads to a wide spectrum of liver injury, including self-limited acute hepatitis, fulminant hepatitis, and chronic hepatitis with progression to cirrhosis or acute exacerbation to liver failure, as well as an asymptomatic chronic carrier state. Several studies have suggested that the hepatitis B core antigen could be an immunological target of cytotoxic T lympho...